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LA Galaxy will be without David Beckham and Landon Donovan, as the duo prepare to feature for the MLS All Star game with Chelsea.
Former Spurs forward Robbie Keane should feature, the Irishman has scored six goals in seven games since he returned from Euro 2012.
New Tottenham boss Andre Villas-Boas is likely to give another run-out to new signing Gylfi Sigurdsson and fellow new signing Jan Vertonghen may also be involved.
The club have fined Croatian midfielder Luka Modric two weeks' wages, around £80,000, for missing the tour of the United States.
The Spurs manager wants the situation resolved as quickly as possible.
"The situation is not dependent on Tottenham, it is dependent on the clubs who are interested in the player.
"It's the first time Luka has taken these actions. The chairman and myself have been very open with the situation by saying we are willing to listen to offers for the player, which is uncommon.
"We never doubt his human qualities but the club has to take action regarding a player who is missing on club duty and that's what we are doing.
"We have to hold on to our values and our rights and at the moment, the situation for Luka is that he is under club discipline.
"Unfortunately for him he is going to have to be fined by the club for not being present.
"He is a player who has offered so much to Tottenham so we have to have a sense of respect for what he has done over the years for us, but the chairman feels that the fact he is not present is not common professional behaviour
"Hopefully the situation can be solved in one of two ways - the two ways being that the clubs interested meet the demands of Tottenham regarding the player's value, or the player continues and returns to club duty."