I'm personally not a fan of the HQM bandwagon trend, as I think that many people throw it in when it isn't needed just to be part of the popular group. However many people do enjoy it. So, in the interest of fairness, I'll point out that there are many ways to use it. For instance, you can throw in repeatable quests, with or without a forced delay on how often they can be turned in. You can have quests with no prerequisites. You can have hidden quests that only reveal themselves when the player has already met the requirements to turn them in. Balancing can be tricky, but there are many ways to use the Quest Book. Some mods use it as a shopping catalogue, with quests that require a currency item of some kind be consumed. Some use it more or less just as a tutorial. Or you could use it as a "bounty board" of sorts, rewarding players for successful hunts. Or have it track important milestones. Or combine any of those, and/or anything else you can come up with.
Or, go with your instinct. If you think it's an awkward fit, it might not be best to include. There are probably other ways to help players along. Maybe a combination of the mod that lets you customize loot and a required/recommended bonus chest? Or, if you have/know anyone with the skills, maybe make/get a custom mod for your pack that can disable certain things until a condition has been met, time or progression, to let players get set up. Or do something completely different. Ultimately, it is your modpack.
Edit: As a side note, after having played Regrowth on the FTB launcher for a bit, I have a word of warning about Ender Zoo. It might just be that Regrowth messes with the spawn rates, but I found it to be one of the most annoying mods to play with. Not in terms of difficulty, but due to two things in particular. Firstly, that the little miniature endermen were attacking creepers constantly, and invariably just causing them to blow up. Even with mob griefing turned off, it's meant having random explosions going off all the time. The second problem is dire wolves. This one was certainly exacerbated by tweaks to spawning, but besides being an almost excessively tough mob (at least in that pack), they're also just plain loud. They howl a lot, and the howl sound effect is at a boosted volume that, even with the game sound turned way down, and my speaker turned down, scared my flatmate in the other room...with their T.V. on.
Ya, I could use HQM for something akin to a tutorial, but I would not want to use it for anything more then that. I like the open ended game-play that Minecraft usually encourages. I like HQM on custom maps where the design is to be more structured, but my pack is more designed to be usable on any random seed, and if I am only using HQM for a tutorial then it is being used for a vary small portion of the packs progression and it capacities are being greatly under utilized. So another option may be better.
My testing with EnderZoo's mobs does not seem to line up with what you experienced with Regrowth, so it must have been things they did. I could not get the EnderMinis to not be able to kill their Creeper targets (only thing that might work is breaking line of sight but that stops the Creepers from exploding), and DIrewolfs are rare and did not seam THAT loud.
-Decreased the dye drop rate for ChromatiCraft trees from 100% to 20% in its configs, because that was too much. *coughrainbowtreescough* Not sure if it worked...
-Disabled EviroMine Village Mineshafts, they like to clip other buildings and make it to easy to get to low Y levels.
-Toned down ambient torch temperature, getting heatstroke from your main light source as fast as you do is a bit much.
-Added crafting Fresh Water from Water Clay Bucket.
-Made Lava Clay Bucket affect the player like a normal Lava Bucket.
-Moved the Status Effect to the left side so as to not conflict with ChromatiCraft information.
-Made most Big Reactor parts immune to EviroMine Physics, it made building them more challenging then is necessary.
-Removed the custom Capacitor upgrade recipes. Ender IO now has its own, more expensive versions.
-Fixed the accidental removal of the silent Dark Pressure Plate recipe.
-Added preliminary Mob Essence to Liquid XP Vat recipe. 1-to-1 experience value ratio at the moment. 1000mb Mob Essence = 300mb Liquid XP.
-Made GeoStrata cobbles grind-able in the SAG Mill just like vanilla cobble.
Seeing as consistency is one of my goals with this pack I have done a little work on a Material Consistency Guideline for recipe editing. Basically all I have done at this point is look at Ender IO's vanilla recipes and see how they are used as a guideline, this will be especially useful for Mods that use only vanilla materials in their recipes or if I think somethings vanilla recipe is to easy (Enhanced Portals 3 for instance in both cases).
Iron - Low grade structural component
Steel - Normal grade structural component
Dark Steel - Advanced grade structural component
Electrical Steel - Electrical grade structural component
Conductive Iron - Weak power conduction
Pulsing Iron - Conduit for transpatial (Ender) energies
Pulsing Crystal - Focus for weak transpatial (Ender) energies
Energetic Alloy - Power storage and universal conduction
Vibrant Alloy - Hyper power storage and conduction
Vibrant Crystal - Power storage and focusing
Soularium - Soul energy (exp) storage and channeling
Ender Crystal - Focus for strong transpatial (Ender) energies
I'm going to put this under Help & Information so everyone can see, discuss, and contribute.
-Fixed MFR Chunk Loader recipe.
-Added crafting the Davy Lamp out of Aluminum Brass.
-Made some Enhanced Portals recipes harder, and more consistent with the rest of the pack.
-Added crafting recipes for Bibliocraft to use Aluminum Brass instead of gold.
-Added enviromine stats to more foods.
-Added Storage Drawers by jaquadro.
-Updated Forge to 10.13.3.1428
Sorry for being inactive for almost 2 months, end of the school year plus getting a new laptop that is not a craptop, I got distracted... It is no excuse and I am sorry.
Ok... it has been a year and four months... I am really bad at this....
While I do not have full recollection what caused me to pause working on this, I do know what some of the causes were.
1) The new Minecraft versions and the wait for updates, this was a bad idea and I should have just kept working until I thought I could move versions.
2) My computer updating itself to Windows 10 due to the timed update popping up while I was AFK* and me having to scramble to try and recover my Patch Notes for the next update. This was not completely successful and demotivated me long enough for me to get distracted again... combine this with point one and you have the double whammy of wanting to wait for a new stable version to start working on again.
3) My own procrastinative and distract-able tendencies.
With that said, things in 1.10 seam to reaching a point where I am getting the itch to work on this again. So I am going to start again from scratch and will update the OP in a few days.
*While I do not like the way Microsoft pushed the update, I have no complaints about Windows 10 itself.