Oh, wait I just thought of something, do you live next door to anyone and do they have a room on the other side of the wall where you keep your desk?
It could be them watching television or something.
Or it could be Satan trying to make sweet love to his desk, and those are moans and groans coming from the desk.
Serious solution: Move the desk outside your room. Wait for... a day. If you still hear the noise then freak out and use one of the many conventional solutions mentioned in this thread.
Why would the polar express stop at his desk.
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Like that scary as (I guess it censored) piano in Super mario 64!
That's what I did to that one hobo who was annoying me. I still have his body in my basement.Cats.