You will lose details when downsampling, remember. You will be throwing away 75% of the pixels so will be losing 75% of the detail.
On the subject of Wolves, Randomobs say there is a showstopper problem with the wolf/dog textures that completely prevents them enabling wolf and dog textures (even without the issue of having the pack remember the colour skin of animals you have tamed). At the moment it is not a case of "we will have it fixed in a while" but more "we don't think we can actually get it to work at all". Long story short, there will not be any wolf texture support in Randomobs in the near future.